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Welcome to the TaILOR Study

The TaILOR trial aims to study the clinical and cost-effectiveness of a patient-initiated follow-up (PIFU) strategy compared to traditional care pathways in people with inflammatory arthritis treated with long-term immune-suppressing therapies.

Inflammatory arthritis usually prevents people from doing things through causing joints to become swollen and painful, or their spine to become stiff. People with arthritis usually require long term treatment with drugs (medications) that affect their immune systems, because of this these individuals are  typically reviewed in outpatient clinics every 6-12 months to check how participants are and that the drugs that should be helping their arthritis are not causing them different issues. However, many of these appointments are unnecessary as patients are well at the time of follow up.

NHS England has recently proposed that many people with inflammatory arthritis should no longer have routine follow up appointments, but be seen if and when they have a problem related to their arthritis such as a flare – they have called this ‘Patient-Initiated Follow Up’ or PIFU. 

Our aim is to test whether PIFU is better than traditional routine follow-up appointments for patients over 24 months.

 Overview of the TaILOR study in pictures

Taking Part

The study needs to recruit 438 patients with stable inflammatory arthritis to take part. These patients will be from approximately 30 sites typically secondary-care NHS hospitals, community-based NHS rheumatology clinics in the UK. 

Participants will complete questionnaires to collect patient-reported outcomes (PRO). Clinical data will also be collected from the medical notes. Participants will be randomised to PIFU or standard care and will attend clinic appointments as per this allocation. Participants will be in the study for 2 years.

For More Information

British Society for Rheumatology (BSR) have developed a number of resources about PIFU for patients.  These can be accessed via our For Patient Page 

For Patients | OCTRU

 

Recruitment Progress:

438
28

Date of latest recruit:

15 May, 2025

Site of latest recruit:

W107H - NHS Western Isles
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Contact Us

Experimental Medicine & Rheumatology Trials Group Oxford Clinical Trials Research Unit (OCTRU) 

Botnar Research Centre, NDORMS University of Oxford
Windmill Road
Headington
Oxford, OX3 7LD

Email

Trial Email: tailor@ndorms.ox.ac.uk 

Call Us: 01865 613739

 

Funded By

TaILOR is funded by the NIHR I National Institute for Health and Care Research 

 

Sponsor

TaILOR is sponsored by the University of Oxford